Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRS | Q13332 | 7/20 | 0.53 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 3/20 | 0.53 |
| ▸ | BLM | P54132 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | HBB | P68871 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | GALK1 | P51570 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.51 |
| ▸ | AKT1 | P31749 | 2/20 | 0.49 |
| ▸ | GABRP | O00591 | 2/20 | 0.49 |
| ▸ | GABRD | O14764 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1977221 | 1.00 | PTPRS (0.53) | PTPRSFTOKMT2AKDM4EMEN1 | |
| SCHEMBL1977462 | 0.90 | AKT1 (0.63) | FTOKMT2AKDM4EMEN1MAPT | |
| SCHEMBL1976105 | 0.90 | AKT1 (0.63) | FTOKMT2AKDM4EMEN1MAPT | |
| SCHEMBL1974890 | 0.88 | KMT2A (0.63) | PTPRSFTOKMT2AKDM4EMEN1 | |
| SCHEMBL1975145 | 0.88 | KMT2A (0.63) | PTPRSFTOKMT2AKDM4EMEN1 | |
| SCHEMBL1973575 | 0.87 | KDM4E (0.53) | PTPRSFTOKMT2AKDM4EMEN1 | |
| SCHEMBL1977889 | 0.87 | KDM4E (0.53) | PTPRSFTOKMT2AKDM4EMEN1 | |
| SCHEMBL1974043 | 0.84 | AKT1 (0.48) | PTPRSFTOKMT2AKDM4EMEN1 | |
| SCHEMBL1977046 | 0.84 | AKT1 (0.48) | PTPRSFTOKMT2AKDM4EMEN1 | |
| SCHEMBL11662442 | 0.78 | PTPRS (0.74) | PTPRSFTOKMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110144194-A1 | CHROMENONE DERIVATIVES USEFUL FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | AXOGLIA THERAPEUTICS (LU) | 2011-06-16 | — | — | US | disclosed |
| EP-2112145-A1 | Chromenone derivatives useful for the treatment of neurodegenerative diseases | AxoGlia Therapeutics S.A. (LU) | 2009-10-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144194-A1 | CHROMENONE DERIVATIVES USEFUL FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | PARK7, CDR2, SNCA | PTPRS 4256/4885FTO 4209/4885KMT2A 3801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.