Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL159994 | 1.00 | HSD11B1 (0.47) | HSD11B1GLAL3MBTL1EPHX1CA2 | |
| Acetic Acid SCHEMBL27574386 | 0.95 | HSD11B1 (0.44) | HSD11B1GLAL3MBTL1EPHX1CA2 | |
| SCHEMBL21904429 | 0.88 | — | — | |
| SCHEMBL24856804 | 0.87 | HSD11B1 (0.38) | HSD11B1GLAL3MBTL1EPHX1CA2 | |
| Formic Acid Methyl Ester SCHEMBL27560711 | 0.85 | GLA (0.46) | HSD11B1GLAL3MBTL1EPHX1CA2 | |
| SCHEMBL5356850 | 0.84 | SMN1; SMN2 (0.50) | HSD11B1GLAL3MBTL1ALDH1A1LMNA | |
| SCHEMBL19798637 | 0.82 | CYP2C9 (0.37) | HSD11B1GLAL3MBTL1EPHX1CA2 | |
| SCHEMBL19808523 | 0.82 | HSD11B1 (0.35) | HSD11B1GLAL3MBTL1EPHX1CA2 | |
| SCHEMBL6495033 | 0.80 | EPHX2 (0.50) | HSD11B1GLAL3MBTL1ALDH1A1EPHX2 | |
| SCHEMBL18028880 | 0.80 | HSD11B1 (0.34) | HSD11B1GLAL3MBTL1EPHX1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9856254-B2 | Alkoxy substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-01-02 | — | — | US | disclosed |