Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.55 |
| ▸ | MME | P08473 | 3/20 | 0.55 |
| ▸ | F2 | P00734 | 3/20 | 0.55 |
| ▸ | F7 | P08709 | 2/20 | 0.55 |
| ▸ | F3 | P13726 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL197912 | 1.00 | ACE (0.55) | ACEMMEF2F7F3 | |
| SCHEMBL197586 | 1.00 | ACE (0.55) | ACEMMEF2F7F3 | |
| Bromide SCHEMBL7442462 | 0.99 | ACE (0.54) | ACEMMEF2F7F3 | |
| Bromide SCHEMBL7442458 | 0.99 | ACE (0.54) | ACEMMEF2F7F3 | |
| SCHEMBL9802560 | 0.89 | F2 (0.55) | ACEMMEF2F7F3 | |
| SCHEMBL9802556 | 0.89 | F2 (0.55) | ACEMMEF2F7F3 | |
| SCHEMBL7342590 | 0.87 | ACE (0.57) | ACEMMEF2F7F3 | |
| SCHEMBL11066807 | 0.85 | LMNA (0.54) | ACEMMEF2F7F3 | |
| SCHEMBL12893380 | 0.84 | ACE (0.55) | ACEMMEF2KMT2AMITF | |
| SCHEMBL8881927 | 0.83 | NPSR1 (0.65) | ACEMMEF2F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088890-B2 | Peptides and peptidomimetic compounds, the manufacturing thereof as well as their use for preparing a therapeutically and/or preventively active pharmaceutical composition | FIBREX MEDICAL RESEARCH & DEVELOPMENT GMBH (AT) | 2012-01-03 | — | — | US | claimed |