SCHEMBL19759249

SCHEMBL19759249

C=CC(=O)OCOc1ccc(C(=O)Oc2ccc(OC(=O)c3ccc(OCOC(=O)C=C)cc3)c(OCOC(=O)C=C)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.39
KMT2A Q03164 7/20 0.39
MEN1 O00255 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
CYP3A4 P08684 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MAPT P10636 5/20 0.37
KDM4E B2RXH2 1/20 0.37
POLB P06746 1/20 0.37
MAPK1 P28482 1/20 0.37
PRSS1 P07477 1/20 0.35
ACR P10323 1/20 0.35
CCNC P24863 1/20 0.34
CDK8 P49336 1/20 0.34
GBA1 P04062 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12733816 0.96 THRB (0.40) THRBKMT2AMEN1TDP1CYP3A4
SCHEMBL12242827 0.93 THRB (0.37) THRBKMT2AMEN1TDP1MAPT
SCHEMBL16449838 0.92 KMT2A (0.50) THRBKMT2AMEN1TDP1CYP3A4
SCHEMBL15946522 0.90 KMT2A (0.39) THRBKMT2AMEN1CYP3A4MAPT
SCHEMBL19759256 0.90 MAPT (0.40) THRBKMT2AMEN1MAPTKDM4E
SCHEMBL12733741 0.90 KMT2A (0.48) THRBKMT2AMEN1TDP1CYP3A4
SCHEMBL16449869 0.89 THRB (0.38) THRBKMT2AMEN1TDP1CYP3A4
SCHEMBL19759246 0.89 THRB (0.40) THRBKMT2AMEN1MAPTKDM4E
SCHEMBL12733841 0.88 MAPT (0.43) THRBKMT2AMEN1TDP1CYP3A4
SCHEMBL12733822 0.88 THRB (0.37) THRBKMT2AMEN1TDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11697695-B2 Polymerizable composition and optically anisotropic body using same DIC CORPORATION (JP) 2023-07-11 US disclosed
US-20180112022-A1 POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC MATERIAL DIC CORPORATION (JP) 2018-04-26 US disclosed
US-20180066189-A1 POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY USING SAME DIC CORPORATION (JP) 2018-03-08 US disclosed
US-20180031738-A1 RETARDATION PLATE AND CIRCULARLY POLARIZING PLATE DIC CORPORATION (JP) 2018-02-01 US disclosed
US-20180016502-A1 POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY USING SAME DIC CORPORATION (JP) 2018-01-18 US disclosed
US-20180002459-A1 POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY USING SAME DIC CORPORATION (JP) 2018-01-04 US disclosed
US-20180002460-A1 POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY USING SAME DIC CORPORATION (JP) 2018-01-04 US disclosed