Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 11/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | PKM | P14618 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | RORC | P51449 | 9/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.82 |
| ▸ | HPGD | P15428 | 1/20 | 0.82 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | CASP1 | P29466 | 1/20 | 0.72 |
| ▸ | CASP7 | P55210 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29437328 | 1.00 | BRD4 (1.00) | BRD4ALDH1A1PKMSMN1; SMN2MEN1 | |
| SCHEMBL16866292 | 0.96 | BRD4 (0.92) | BRD4ALDH1A1PKMSMN1; SMN2MEN1 | |
| SCHEMBL16866211 | 0.96 | BRD4 (0.92) | BRD4ALDH1A1PKMSMN1; SMN2MEN1 | |
| SCHEMBL16862799 | 0.92 | BRD4 (0.84) | BRD4ALDH1A1PKMSMN1; SMN2MEN1 | |
| SCHEMBL16862772 | 0.91 | RORC (1.00) | BRD4ALDH1A1PKMSMN1; SMN2MEN1 | |
| SCHEMBL16862773 | 0.91 | RORC (1.00) | BRD4ALDH1A1PKMSMN1; SMN2MEN1 | |
| SCHEMBL29437305 | 0.90 | BRD4 (1.00) | BRD4ALDH1A1PKMSMN1; SMN2MEN1 | |
| SCHEMBL16862811 | 0.90 | BRD4 (1.00) | BRD4ALDH1A1PKMSMN1; SMN2MEN1 | |
| SCHEMBL17992504 | 0.90 | BRD4 (1.00) | BRD4ALDH1A1PKMSMN1; SMN2MEN1 | |
| SCHEMBL29437336 | 0.90 | BRD4 (1.00) | BRD4ALDH1A1PKMSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10183010-B2 | 2-oxo-1,2-dihydrobenzo[cd]indole compound and use thereof | GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2019-01-22 | — | — | US | disclosed |
| US-20180008574-A1 | 2-oxo-1,2-dihydrobenzo[cd]indole compound and use thereof | GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2018-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180008574-A1 | 2-oxo-1,2-dihydrobenzo[cd]indole compound and use thereof | BRD4, BRD3, BRD1 | BRD4 1/4885ALDH1A1 3416/4885PKM 4676/4885 |
| US-10183010-B2 | 2-oxo-1,2-dihydrobenzo[cd]indole compound and use thereof | BRD4, BRD3, BRD1 | BRD4 1/4885ALDH1A1 3416/4885PKM 4676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.