Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 6/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 11/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | RBP4 | P02753 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16371852 | 0.87 | P2RX7 (0.44) | HCRTR1P2RX7GRM5 | |
| SCHEMBL17799684 | 0.87 | P2RX7 (0.44) | HCRTR1P2RX7GRM5 | |
| SCHEMBL19767312 | 0.86 | HCRTR1 (0.41) | HCRTR1P2RX7GRM5 | |
| SCHEMBL16372435 | 0.84 | ACKR3 (0.42) | HCRTR1P2RX7 | |
| SCHEMBL19771728 | 0.84 | ACKR3 (0.42) | HCRTR1P2RX7 | |
| SCHEMBL24543387 | 0.84 | ACKR3 (0.42) | HCRTR1P2RX7 | |
| SCHEMBL30704818 | 0.84 | ACKR3 (0.42) | HCRTR1P2RX7 | |
| SCHEMBL21273819 | 0.84 | ACKR3 (0.42) | HCRTR1P2RX7 | |
| SCHEMBL21273811 | 0.84 | ACKR3 (0.42) | HCRTR1P2RX7 | |
| SCHEMBL29367888 | 0.84 | ACKR3 (0.42) | HCRTR1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019476-B1 | 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-01-17 | — | — | EP | disclosed |
| US-9867371-B2 | 4-membered ring carboxamides used as nematicides | SYNGENTA PARTICIPATIONS AG (CH) | 2018-01-16 | — | — | US | disclosed |