Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1976731 | 1.00 | KDM1A (0.49) | KDM1ATBXAS1PKMHRH3MAOB | |
| SCHEMBL1976735 | 1.00 | KDM1A (0.49) | KDM1ATBXAS1PKMHRH3MAOB | |
| SCHEMBL1976486 | 0.89 | HRH3 (0.59) | TBXAS1HRH3MAOB | |
| SCHEMBL1976489 | 0.89 | HRH3 (0.59) | TBXAS1HRH3MAOB | |
| SCHEMBL1976491 | 0.89 | HRH3 (0.59) | TBXAS1HRH3MAOB | |
| Hydrochloric Acid SCHEMBL13583752 | 0.89 | HRH3 (0.45) | HRH3MAOB | |
| Hydrochloric Acid SCHEMBL13583749 | 0.89 | HRH3 (0.45) | HRH3MAOB | |
| Hydrochloric Acid SCHEMBL13583751 | 0.89 | HRH3 (0.45) | HRH3MAOB | |
| Hydrochloric Acid SCHEMBL13583125 | 0.88 | HRH3 (0.58) | TBXAS1HRH3MAOB | |
| Hydrochloric Acid SCHEMBL13583122 | 0.88 | HRH3 (0.58) | TBXAS1HRH3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120283245-A1 | AZABICYCLO[3.1.0]HEX-2-YL COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2012-11-08 | — | — | US | disclosed |
| EP-2509947-A1 | AZABICYCLO[3.1.0]HEX-2-YL DERIVATIVES, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Les Laboratoires Servier (FR) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011070253-A1 | AZABICYCLO[3.1.0]HEX-2-YL DERIVATIVES, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2011-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283245-A1 | AZABICYCLO[3.1.0]HEX-2-YL COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AGER, AZI2, HTT | KDM1A 55/4885TBXAS1 2174/4885PKM 3209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.