SCHEMBL19769481

SCHEMBL19769481

c1ccc(-n2c3ccccc3c3ccc4c5ccccc5n(-c5ccc(-c6ccc7c8ccccc8n(-c8cccc9ccccc89)c7c6)cc5)c4c32)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.42
ATM Q13315 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ALDH1A1 P00352 3/20 0.35
TDP1 Q9NUW8 1/20 0.35
HDAC4 P56524 1/20 0.34
PDE6D O43924 1/20 0.34
RXRA P19793 1/20 0.34
RXRB P28702 1/20 0.34
PTGS1 P23219 1/20 0.33
PTGS2 P35354 1/20 0.33
HPGD P15428 1/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
KHK P50053 1/20 0.33
KMT2A Q03164 1/20 0.32
GSK3A P49840 1/20 0.32
GSK3B P49841 1/20 0.32
IL1R1 P14778 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19769464 0.97 KDM4E (0.46) KDM4EATML3MBTL1ALDH1A1TDP1
SCHEMBL19769479 0.94 KDM4E (0.41) KDM4EATML3MBTL1ALDH1A1TDP1
SCHEMBL19653190 0.93 L3MBTL1 (0.41) KDM4EATML3MBTL1ALDH1A1TDP1
SCHEMBL19769476 0.92 L3MBTL1 (0.39) KDM4EATML3MBTL1ALDH1A1TDP1
SCHEMBL23862253 0.91 L3MBTL1 (0.44) KDM4EATML3MBTL1ALDH1A1TDP1
SCHEMBL23862327 0.91 L3MBTL1 (0.44) KDM4EATML3MBTL1ALDH1A1TDP1
SCHEMBL19769583 0.91 L3MBTL1 (0.47) KDM4EATML3MBTL1ALDH1A1TDP1
SCHEMBL19769584 0.91 L3MBTL1 (0.47) KDM4EATML3MBTL1ALDH1A1TDP1
SCHEMBL18779492 0.91 L3MBTL1 (0.50) KDM4EATML3MBTL1ALDH1A1TDP1
SCHEMBL22505070 0.91 KDM4E (0.46) KDM4EATML3MBTL1ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180019409-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-18 US disclosed
US-20180019409-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180019409-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OR10J3, OR51E2, OXER1 KDM4E 4452/4885ATM 4365/4885L3MBTL1 4794/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.