SCHEMBL19769828

SCHEMBL19769828

c1ccc(-c2cccc(-c3cc(-c4cccc(-c5ccccc5)c4)nc(-n4c5ccccc5c5cc6c(cc54)c4ccccc4n6-c4ccccc4)n3)c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.47
KDM4E B2RXH2 3/20 0.47
ATM Q13315 1/20 0.47
KMT2A Q03164 4/20 0.35
IL1R1 P14778 1/20 0.35
MAPT P10636 3/20 0.35
MEN1 O00255 3/20 0.35
HTT P42858 2/20 0.35
ALDH1A1 P00352 2/20 0.35
MAPK1 P28482 2/20 0.34
RXFP1 Q9HBX9 1/20 0.34
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33
HDAC4 P56524 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TET2 Q6N021 1/20 0.32
TET1 Q8NFU7 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19769824 0.99 KDM4E (0.46) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL19769827 0.97 KDM4E (0.45) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL19769721 0.96 L3MBTL1 (0.46) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL19769705 0.95 KDM4E (0.45) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL19769725 0.94 KDM4E (0.44) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL15748511 0.94 L3MBTL1 (0.46) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL17809384 0.94 KDM4E (0.42) L3MBTL1KDM4EATMKMT2AMAPT
SCHEMBL6374961 0.93 L3MBTL1 (0.43) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL23972171 0.92 KDM4E (0.45) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL15626409 0.92 KDM4E (0.45) L3MBTL1KDM4EATMKMT2AIL1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10505126-B2 Composition for organic optoelectric device and organic optoelectric device and display device SAMSUNG SDI CO., LTD. (KR) 2019-12-10 US disclosed
US-20180026204-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-25 US disclosed
US-20180026204-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-25 US disclosed
US-20180019409-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-18 US disclosed
US-20180019409-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180019409-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OR10J3, OR51E2, OXER1 L3MBTL1 4794/4885KDM4E 4452/4885ATM 4365/4885
US-10505126-B2 Composition for organic optoelectric device and organic optoelectric device and display device OXER1, OR10J3, OR51E2 L3MBTL1 4812/4885KDM4E 4531/4885ATM 4381/4885
US-20180026204-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE OXER1, OR10J3, OR51E2 L3MBTL1 4812/4885KDM4E 4531/4885ATM 4381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.