SCHEMBL19769860

SCHEMBL19769860

c1ccc(-c2cccc(-c3cc(-c4cccc(-c5ccccc5)c4)nc(-n4c5ccccc5c5ccc6c(c7ccccc7n6-c6ccccc6)c54)n3)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
RXFP1 Q9HBX9 1/20 0.33
JAK2 O60674 1/20 0.33
JAK3 P52333 1/20 0.33
KMT2A Q03164 3/20 0.32
IL1R1 P14778 1/20 0.32
MEN1 O00255 2/20 0.31
GAA P10253 1/20 0.31
HTT P42858 2/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
MAPK1 P28482 1/20 0.30
AKR1C3 P42330 1/20 0.30
AKR1C2 P52895 1/20 0.30
AKR1C1 Q04828 1/20 0.30
NR3C1 P04150 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19769862 0.99 L3MBTL1 (0.40) L3MBTL1KDM4EATMRXFP1JAK2
SCHEMBL19769866 0.98 KDM4E (0.39) L3MBTL1KDM4EATMRXFP1JAK2
SCHEMBL19769898 0.95 L3MBTL1 (0.38) L3MBTL1KDM4EATMRXFP1JAK2
SCHEMBL19769894 0.94 KDM4E (0.37) L3MBTL1KDM4EATMRXFP1JAK2
SCHEMBL19769897 0.93 KDM4E (0.36) L3MBTL1KDM4EATMRXFP1KMT2A
SCHEMBL21018133 0.93 L3MBTL1 (0.38) L3MBTL1KDM4EATMRXFP1KMT2A
SCHEMBL19769865 0.93 L3MBTL1 (0.43) L3MBTL1KDM4EATMRXFP1JAK2
SCHEMBL19769859 0.93 L3MBTL1 (0.43) L3MBTL1KDM4EATMRXFP1JAK2
SCHEMBL12131957 0.93 L3MBTL1 (0.45) L3MBTL1KDM4EATMRXFP1JAK2
SCHEMBL21018134 0.92 L3MBTL1 (0.40) L3MBTL1KDM4EATMRXFP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10505126-B2 Composition for organic optoelectric device and organic optoelectric device and display device SAMSUNG SDI CO., LTD. (KR) 2019-12-10 US disclosed
US-20180026204-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-25 US disclosed
US-20180026204-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-25 US disclosed
US-20180019409-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-18 US disclosed
US-20180019409-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180019409-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OR10J3, OR51E2, OXER1 L3MBTL1 4794/4885KDM4E 4452/4885ATM 4365/4885
US-10505126-B2 Composition for organic optoelectric device and organic optoelectric device and display device OXER1, OR10J3, OR51E2 L3MBTL1 4812/4885KDM4E 4531/4885ATM 4381/4885
US-20180026204-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE OXER1, OR10J3, OR51E2 L3MBTL1 4812/4885KDM4E 4531/4885ATM 4381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.