SCHEMBL19769876

SCHEMBL19769876

c1ccc(-c2cccc(-c3nc(-c4ccc5c(c4)oc4ccccc45)nc(-n4c5ccccc5c5ccc6c(c7ccccc7n6-c6ccccc6)c54)n3)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.35
KDM4E B2RXH2 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MMP12 P39900 1/20 0.32
MMP13 P45452 1/20 0.32
PLA2G2A P14555 2/20 0.32
PLA2G4A P47712 2/20 0.32
HCRTR1 O43613 1/20 0.31
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
PLA2G10 O15496 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23602177 0.96 MMP12 (0.32) ATMKDM4EL3MBTL1MMP12MMP13
SCHEMBL22050477 0.96 KDM4E (0.36) ATMKDM4EL3MBTL1MMP12MMP13
SCHEMBL20315870 0.95 MMP12 (0.32) ATMKDM4EL3MBTL1MMP12MMP13
SCHEMBL19769871 0.95 KDM4E (0.37) ATMKDM4EL3MBTL1MMP12MMP13
SCHEMBL23602170 0.95 KDM4E (0.37) ATMKDM4EL3MBTL1MMP12MMP13
SCHEMBL23602246 0.95 KDM4E (0.38) ATMKDM4EL3MBTL1MMP12MMP13
SCHEMBL26473046 0.94 KDM4E (0.32) ATMKDM4EL3MBTL1MMP12MMP13
SCHEMBL20315896 0.94 KDM4E (0.33) ATMKDM4EL3MBTL1MMP12MMP13
SCHEMBL25010835 0.93 MMP12 (0.32) ATMMMP12MMP13PLA2G2APLA2G4A
SCHEMBL24914542 0.93 KDM4E (0.34) ATMKDM4EL3MBTL1PLA2G2APLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10505126-B2 Composition for organic optoelectric device and organic optoelectric device and display device SAMSUNG SDI CO., LTD. (KR) 2019-12-10 US disclosed
US-20180026204-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-25 US disclosed
US-20180026204-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-25 US disclosed
US-20180019409-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-18 US disclosed
US-20180019409-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180019409-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OR10J3, OR51E2, OXER1 ATM 4365/4885KDM4E 4452/4885L3MBTL1 4794/4885
US-10505126-B2 Composition for organic optoelectric device and organic optoelectric device and display device OXER1, OR10J3, OR51E2 ATM 4381/4885KDM4E 4531/4885L3MBTL1 4812/4885
US-20180026204-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE OXER1, OR10J3, OR51E2 ATM 4381/4885KDM4E 4531/4885L3MBTL1 4812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.