SCHEMBL19770686

SCHEMBL19770686

S=c1c2ccccc2[nH]c2cc3c(=S)c4ccccc4[nH]c3cc12

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CDK4 P11802 1/20 0.75
▸ CCND1 P24385 1/20 0.75
▸ AHR P35869 1/20 0.67
▸ ALDH1A1 P00352 5/20 0.56
▸ HSD17B10 Q99714 3/20 0.56
▸ GPR3 P46089 1/20 0.56
▸ KIF11 P52732 8/20 0.50
▸ KMT2A Q03164 2/20 0.50
▸ HPGD P15428 3/20 0.48
▸ ALOX15 P16050 2/20 0.48
▸ RXFP1 Q9HBX9 1/20 0.48
▸ KDM4E B2RXH2 2/20 0.48
▸ LMNA P02545 1/20 0.48
▸ GLA P06280 1/20 0.48
▸ GAA P10253 1/20 0.48
▸ HTT P42858 1/20 0.48
▸ ATM Q13315 1/20 0.48
▸ SMN1; SMN2 Q16637 1/20 0.48
▸ TOP2A P11388 1/20 0.43
▸ MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29558542 0.91 ALDH1A1 (0.68) CDK4CCND1AHRALDH1A1HSD17B10
SCHEMBL745474 0.91 ALDH1A1 (0.68) CDK4CCND1AHRALDH1A1HSD17B10
SCHEMBL29814291 0.91 ALDH1A1 (0.68) CDK4CCND1AHRALDH1A1HSD17B10
SCHEMBL29414082 0.86 CDK4 (1.00) CDK4CCND1AHRALDH1A1HSD17B10
SCHEMBL6689351 0.86 CDK4 (1.00) CDK4CCND1AHRALDH1A1HSD17B10
SCHEMBL21064780 0.82 NPC1 (0.64) CDK4CCND1AHRALDH1A1HSD17B10
SCHEMBL18940503 0.80 CDK4 (0.53) CDK4CCND1AHRALDH1A1HSD17B10
SCHEMBL19455080 0.80 CDK4 (0.56) CDK4CCND1AHRALDH1A1HSD17B10
SCHEMBL550602 0.80 AHR (1.00) AHRALDH1A1HSD17B10GPR3KIF11
SCHEMBL12219478 0.80 AHR (1.00) AHRALDH1A1HSD17B10GPR3KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3251152-B1 DETECTOR FOR AN OPTICAL DETECTION OF AT LEAST ONE OBJECT TRINAMIX GMBH (DE) 2023-08-16 — — EP disclosed
US-10775505-B2 Detector for an optical detection of at least one object TRINAMIX GMBH (DE) 2020-09-15 — — US disclosed
US-20190140129-A1 DETECTOR FOR AN OPTICAL DETECTION OF AT LEAST ONE OBJECT TRINAMIX GMBH (DE) 2019-05-09 — — US disclosed
US-20180017679-A1 DETECTOR FOR AN OPTICAL DETECTION OF AT LEAST ONE OBJECT TRINAMIX GMBH (DE) 2018-01-18 — — US disclosed
US-20180017679-A1 DETECTOR FOR AN OPTICAL DETECTION OF AT LEAST ONE OBJECT TRINAMIX GMBH (DE) 2018-01-18 — — US disclosed
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