SCHEMBL19771

SCHEMBL19771

Fc1[c]ccc(Br)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27813885 0.91
SCHEMBL1491004 0.75 ALDH1A1 (0.39)
SCHEMBL7861005 0.72
SCHEMBL15066583 0.72 CYP2A6 (0.32)
SCHEMBL3465 0.72
SCHEMBL17514911 0.72 ESR1 (0.31)
SCHEMBL21630325 0.71 MAPT (0.44)
Hydrochloric Acid SCHEMBL22092309 0.70
SCHEMBL27458087 0.70
SCHEMBL27436100 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4019 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118290379-A Preparation method of novel agricultural multifunctional substance and application of novel agricultural multifunctional substance in aspects of resisting virus, inhibiting bacteria and promoting plant growth 贵州工业职业技术学院 2024-07-05 CN claimed
WO-2024102177-A1 COMBINATION THERAPIES FOR THE TREATMENT OF BRAIN CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-05-16 WO claimed
WO-2024081447-A1 EGFR INHIBITORS FOR TREATING LUNG CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-04-18 WO claimed
CN-112004813-B Oxadiazole compounds for controlling phytopathogenic fungi PI工业有限公司 2024-03-29 CN claimed
WO-2023244639-A1 METHODS OF PREDICTING CNS CANCER RESPONSE TO TREATMENT WITH EGFR INHIBITORS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-12-21 WO claimed
US-20230381142-A1 ANTILEISHMANIAL COMPOUNDS, COMPOSITIONS AND USE THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2023-11-30 US claimed
WO-2023230217-A1 ANTILEISHMANIAL COMPOUNDS, COMPOSITIONS AND USE THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2023-11-30 WO claimed
US-11712438-B2 Phenyl derivatives as PGE2 receptor modulators IDORSIA PHARMACEUTICALS LTD (CH) 2023-08-01 US claimed
WO-2023113114-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING OVERACTIVE BLADDER 광주과학기술원 2023-06-22 WO claimed
US-20230183248-A1 PYRROLO[1,2-D][1,2,4]TRIAZINE-2-YL-ACETAMIDES AS INHIBITORS OF THE NLRP3 INFLAMMASOME PATHWAY JANSSEN PHARMACEUTICA NV (BE) 2023-06-15 US claimed
EP-0401981-B1 Pyridazinone deriratives PFIZER (US) 1995-04-26 EP claimed
EP-0568540-A1 2,4-DIOXO-PYRIDO 2,3-d]PYRIMIDINE-3-ACETIC ACIDS AND ESTERS AND SALTS THEREOF PFIZER INC. (US) 1993-11-10 EP claimed
WO-1992012979-A1 2,4-DIOXO-PYRIDO [2,3-d]PYRIMIDINE-3-ACETIC ACIDS AND ESTERS AND SALTS THEREOF PFIZER INC. (US) 1992-08-06 WO claimed
US-4996204-A Antidiabetic agents PFIZER INC. (US) 1991-02-26 US claimed
EP-0401981-A1 Pyridazinone deriratives PFIZER INC. (US) 1990-12-12 EP claimed
US-4859228-A Novel 5-aminomethylene-2,4-imidazolidinediones and 5-aminomethylene-2-thionoimidazolidine-4-ones ICI AMERICAS INC (US) 1989-08-22 US claimed
EP-0300882-A2 Novel 5-Aminomethylene-2,4-imidazolidinediones and 5-aminomethylene-2-thionoimidazolidine-4-ones ICI AMERICAS INC. (US) 1989-01-25 EP claimed
US-4544662-A ALDOSE REDUCTASE INHIBITORS IMPERIAL CHEMICAL INDUSTRIES (GB) 1985-10-01 US claimed
EP-0094184-A1 Indoline derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-11-16 EP claimed
US-4216232-A Pharmaceutical compositions BEECHAM GROUP LIMITED (GB) 1980-08-05 US claimed