Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 19/20 | 0.52 |
| ▸ | ACE | P12821 | 4/20 | 0.52 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19705879 | 0.90 | MME (0.48) | MMEACEMMEL1 | |
| SCHEMBL18685543 | 0.90 | MME (0.67) | MMEACEMMEL1 | |
| SCHEMBL23055274 | 0.90 | MME (0.67) | MMEACEMMEL1 | |
| SCHEMBL18922667 | 0.87 | MME (0.51) | MMEACEMMEL1 | |
| SCHEMBL19688029 | 0.87 | MME (0.51) | MMEACEMMEL1 | |
| SCHEMBL19771825 | 0.85 | MME (0.55) | MMEACEMMEL1 | |
| SCHEMBL18685531 | 0.85 | MME (0.55) | MMEACEMMEL1 | |
| SCHEMBL19788083 | 0.83 | MME (0.56) | MMEACEMMEL1 | |
| SCHEMBL24350779 | 0.83 | MME (0.56) | MMEACEMMEL1 | |
| SCHEMBL19687852 | 0.82 | MME (0.45) | MMEACEMMEL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9868698-B2 | (2S,4R)-5-(5′-chloro-2′-fluorobiphenyl-4-yl)-4-(ethoxyoxalylamino)-2-hydroxymethyl-2-methylpentanoic acid | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2018-01-16 | — | — | US | disclosed |