Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 19/20 | 0.56 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24350779 | 1.00 | MME (0.56) | MMEMMEL1ACE | |
| SCHEMBL20681821 | 0.93 | MME (0.57) | MMEMMEL1ACE | |
| SCHEMBL15467594 | 0.93 | MME (0.57) | MMEMMEL1ACE | |
| SCHEMBL21350801 | 0.93 | MME (0.54) | MMEMMEL1ACE | |
| SCHEMBL20681840 | 0.93 | MME (0.54) | MMEMMEL1ACE | |
| SCHEMBL22019784 | 0.91 | MME (0.54) | MMEMMEL1ACE | |
| SCHEMBL25913677 | 0.91 | MME (0.54) | MMEMMEL1ACE | |
| SCHEMBL15472726 | 0.90 | MME (0.54) | MMEMMEL1ACE | |
| SCHEMBL19788100 | 0.90 | MME (0.54) | MMEMMEL1ACE | |
| SCHEMBL19687915 | 0.90 | MME (0.69) | MMEMMEL1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9873685-B2 | Neprilysin inhibitors | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2018-01-23 | — | — | US | disclosed |