Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18647630 | 0.97 | AKR1C3 (0.40) | AKR1C3MEN1KMT2AKDM4EMAPT | |
| SCHEMBL16810768 | 0.93 | PDK2 (0.39) | AKR1C3MEN1KMT2AKDM4EMAPT | |
| SCHEMBL24794823 | 0.90 | MEN1 (0.38) | AKR1C3MEN1KMT2AKDM4EMAPT | |
| SCHEMBL21742730 | 0.87 | MEN1 (0.48) | MEN1KMT2AKDM4EMAPTTDP1 | |
| SCHEMBL29797986 | 0.87 | MEN1 (0.48) | MEN1KMT2AKDM4EMAPTTDP1 | |
| SCHEMBL26564272 | 0.86 | MAPK14 (0.39) | AKR1C3MEN1KMT2AKDM4EMAPT | |
| SCHEMBL14681538 | 0.85 | AKR1C3 (0.39) | AKR1C3MEN1KMT2AKDM4EMAPT | |
| SCHEMBL29839680 | 0.85 | AKR1C3 (0.39) | AKR1C3MEN1KMT2AKDM4EMAPT | |
| SCHEMBL20434444 | 0.83 | AKR1C3 (0.40) | AKR1C3MEN1KMT2AKDM4EMAPT | |
| SCHEMBL21763509 | 0.83 | MEN1 (0.36) | AKR1C3MEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3080229-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-01-17 | — | — | EP | disclosed |