Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | STK10 | O94804 | 1/20 | 0.34 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20871547 | 0.93 | MEN1 (0.40) | MEN1KMT2AAKR1C3POLBKDM4E | |
| SCHEMBL22920820 | 0.89 | MEN1 (0.39) | MEN1KMT2AAKR1C3POLBKDM4E | |
| SCHEMBL24794823 | 0.87 | MEN1 (0.38) | MEN1KMT2AAKR1C3POLBKDM4E | |
| SCHEMBL22403681 | 0.84 | MEN1 (0.43) | MEN1KMT2APOLBKDM4EMAPT | |
| SCHEMBL25657064 | 0.84 | MEN1 (0.37) | MEN1KMT2AAKR1C3POLBKDM4E | |
| SCHEMBL23696740 | 0.83 | SIRT2 (0.46) | MEN1KMT2AAKR1C3POLBKDM4E | |
| SCHEMBL19773102 | 0.83 | AKR1C3 (0.39) | MEN1KMT2AAKR1C3POLBKDM4E | |
| SCHEMBL18647630 | 0.83 | AKR1C3 (0.40) | MEN1KMT2AAKR1C3POLBKDM4E | |
| SCHEMBL24882969 | 0.81 | MEN1 (0.39) | MEN1KMT2AAKR1C3POLBKDM4E | |
| SCHEMBL24883250 | 0.81 | MEN1 (0.41) | MEN1KMT2APOLBKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3369719-B1 | SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME | LG CHEMICAL LTD (KR) | 2020-02-26 | — | — | EP | disclosed |