⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL384737 | 0.85 | — | — | |
| SCHEMBL1283751 | 0.85 | — | — | |
| SCHEMBL10357572 | 0.82 | ALDH1A1 (0.37) | — | |
| SCHEMBL384605 | 0.82 | — | — | |
| SCHEMBL11145464 | 0.82 | ALDH1A1 (0.37) | — | |
| SCHEMBL28206446 | 0.82 | ALDH1A1 (0.37) | — | |
| SCHEMBL10358156 | 0.82 | ALDH1A1 (0.37) | — | |
| SCHEMBL8812842 | 0.82 | ALDH1A1 (0.37) | — | |
| SCHEMBL4539948 | 0.79 | TSHR (0.35) | — | |
| SCHEMBL19459167 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 532 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024114814-A1 | JAK INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | ONQUALITY PHARMACEUTICALS CHINA LTD (CN) | 2024-06-06 | — | — | WO | claimed |
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | claimed |
| CN-116135229-A | Application of hypocrellin-containing derivative with both peri-position and 2-position being simultaneously substituted in preparation of photodynamic anti-tumor drugs | 中国科学院理化技术研究所 | 2023-05-19 | — | — | CN | claimed |
| EP-3941906-B1 | QUINOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND USES THEREOF FOR THE TREATMENT OF CANCER | LEAD DISCOVERY CENTER GMBH (DE) | 2023-05-03 | — | — | EP | claimed |
| EP-3887371-B1 | ARYL COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF BACTERIAL INFECTION | HOFFMANN LA ROCHE (CH) | 2023-02-22 | — | — | EP | claimed |
| US-20220169616-A1 | QUINOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND USES THEREOF FOR THE TREATMENT OF CANCER | LEAD DISCOVERY CENTER GMBH (DE) | 2022-06-02 | — | — | US | claimed |
| EP-3941906-A1 | QUINOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND USES THEREOF FOR THE TREATMENT OF CANCER | Lead Discovery Center GmbH (DE) | 2022-01-26 | — | — | EP | claimed |
| US-20210309658-A1 | ARYL COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF BACTERIAL INFECTION | HOFFMANN-LA ROCHE INC. (US) | 2021-10-07 | — | — | US | claimed |
| EP-3887371-A1 | ARYL COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF BACTERIAL INFECTION | F. Hoffmann-La Roche AG (CH) | 2021-10-06 | — | — | EP | claimed |
| CN-113166144-A | Aryl compounds for the treatment and prevention of bacterial infections | 豪夫迈·罗氏有限公司 | 2021-07-23 | — | — | CN | claimed |
| US-4581170-A | N-hydroxyl protecting groups and process and intermediates for the preparation of 3-acylamino-1-hydroxy-2-azetidinones | E. R. SQUIBB & SONS, INC. (US) | 1986-04-08 | — | — | US | claimed |
| US-4576749-A | 3-Acylamino-1-carboxymethylaminocarbonyl-2-azetidinones | E. R. SQUIBB & SONS, INC. (US) | 1986-03-18 | — | — | US | claimed |
| EP-0170280-A1 | Novel intermediates and process for the preparation of 3-acylamino-1-hydroxy-2-azetidinones | E.R. Squibb & Sons, Inc. (US) | 1986-02-05 | — | — | EP | claimed |
| US-4559335-A | 3-Acylamino-1-carboxymethyloxy (or thio) carbonyl-2-azetidinones | E. R. SQUIBB & SONS, INC. (US) | 1985-12-17 | — | — | US | claimed |
| US-4551277-A | 4-(3-Acylamino-2-oxo-1-azetidinyl)-4-oxo-2-butenoic acid | E. R. SQUIBB & SONS, INC. (US) | 1985-11-05 | — | — | US | claimed |
| US-4548751-A | (2-Oxo-1-azetidinyloxy)-2-propenoic acid | E. R. SQUIBB & SONS, INC. (US) | 1985-10-22 | — | — | US | claimed |
| EP-0138407-A1 | Azetidinones | E.R. Squibb & Sons, Inc. (US) | 1985-04-24 | — | — | EP | claimed |
| EP-0135814-A1 | 1-(1H-tetrazol-5-ylalkoxy)-2-azetidinones | E.R. Squibb & Sons, Inc. (US) | 1985-04-03 | — | — | EP | claimed |
| EP-0070803-A2 | Antibiotically active aminotriazolylcephalosporin derivatives and their preparation | CIBA-GEIGY AG (CH) | 1983-01-26 | — | — | EP | claimed |
| EP-0022245-A2 | Aminothiadiazolyl derivatives, process for their preparation, pharmaceutical compositions containing them;starting compounds and process for their preparation | CIBA-GEIGY AG (CH) | 1981-01-14 | — | — | EP | claimed |