Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20621285 | 0.89 | L3MBTL1 (0.38) | TSHRALDH1A1HPGDL3MBTL1SMN1; SMN2 | |
| SCHEMBL19768959 | 0.84 | EGFR (0.34) | TSHRHPGDSMN1; SMN2CYP1A2MAPK1 | |
| SCHEMBL23492867 | 0.83 | TSHR (0.34) | TSHRALDH1A1HPGDL3MBTL1SMN1; SMN2 | |
| SCHEMBL21883598 | 0.78 | MAPK1 (0.31) | SMN1; SMN2MAPK1GAAEGFRERBB2 | |
| SCHEMBL10490933 | 0.76 | TSHR (0.41) | TSHRALDH1A1HPGDL3MBTL1SMN1; SMN2 | |
| SCHEMBL21884012 | 0.74 | TSHR (0.38) | TSHRALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL19779785 | 0.74 | TSHR (0.37) | TSHRALDH1A1HPGDL3MBTL1SMN1; SMN2 | |
| SCHEMBL19069126 | 0.74 | TSHR (0.33) | TSHRALDH1A1HPGDL3MBTL1SMN1; SMN2 | |
| SCHEMBL19592244 | 0.74 | AR (0.35) | TSHRALDH1A1HPGDL3MBTL1SMN1; SMN2 | |
| SCHEMBL23269915 | 0.73 | PTPN1 (0.49) | TSHRCYP1A2CYP2D6CYP2C9GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180016252-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. | 2018-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180016252-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | SSTR5, SSTR2, SSTR4 | TSHR 70/4885ALDH1A1 4626/4885HPGD 1517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.