Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.78 |
| ▸ | PARP10 | Q53GL7 | 7/20 | 0.54 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.54 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.51 |
| ▸ | HRH2 | P25021 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.50 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30969254 | 0.94 | HRH3 (0.88) | HRH3PARP10PARP15PARP2TBXAS1 | |
| SCHEMBL1977578 | 0.93 | HRH3 (0.90) | HRH3PARP10PARP15PARP2TBXAS1 | |
| Hydrochloric Acid SCHEMBL1979057 | 0.92 | HRH3 (0.88) | HRH3PARP10PARP15PARP2TBXAS1 | |
| SCHEMBL1979219 | 0.92 | HRH3 (0.83) | HRH3PARP10PARP15PARP2TBXAS1 | |
| SCHEMBL3827146 | 0.91 | HRH3 (0.70) | HRH3PARP10PARP15PARP2TBXAS1 | |
| Oxalic Acid SCHEMBL1976615 | 0.89 | HRH3 (0.83) | HRH3PARP10PARP15PARP2HRH2 | |
| SCHEMBL14152811 | 0.88 | HRH3 (1.00) | HRH3PARP10PARP15PARP2HRH2 | |
| SCHEMBL14158615 | 0.88 | HRH3 (1.00) | HRH3PARP10PARP15PARP2HRH2 | |
| SCHEMBL14152810 | 0.88 | HRH3 (1.00) | HRH3PARP10PARP15PARP2HRH2 | |
| SCHEMBL4489280 | 0.88 | HRH3 (0.95) | HRH3PARP10PARP15PARP2HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2332910-B1 | New derivatives of azabicyclo[3.2.0]hept-3-yl, method for preparing same and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2013-01-30 | — | — | EP | disclosed |
| US-8008337-B2 | Azabicyclo[3.2.0] hept-3-yl compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2011-08-30 | — | — | US | disclosed |
| EP-2332910-A1 | New derivatives of azabicyclo[3.2.0]hept-3-yl, method for preparing same and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2011-06-15 | — | — | EP | disclosed |
| US-20110136886-A1 | Azabicyclo[3.2.0] hept-3-yl compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136886-A1 | Azabicyclo[3.2.0] hept-3-yl compounds, a process for their preparation and pharmaceutical compositions containing them | HRH2, HRH4, HRH3 | HRH3 3/4885PARP10 1138/4885PARP15 1837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.