Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 12/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 11/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 9/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18537605 | 0.98 | EPHX1 (0.53) | EPHX1TAS1R3TAS1R1TAS1R2SMN1; SMN2 | |
| SCHEMBL9505661 | 0.79 | EPHX1 (0.53) | EPHX1TAS1R3TAS1R1TAS1R2SMN1; SMN2 | |
| SCHEMBL23772197 | 0.77 | EPHX1 (0.60) | EPHX1TAS1R3TAS1R1TAS1R2SMN1; SMN2 | |
| SCHEMBL13191370 | 0.77 | EPHX1 (0.60) | EPHX1TAS1R3TAS1R1TAS1R2SMN1; SMN2 | |
| SCHEMBL10331369 | 0.77 | EPHX1 (0.60) | EPHX1TAS1R3TAS1R1TAS1R2SMN1; SMN2 | |
| SCHEMBL23772463 | 0.77 | EPHX1 (0.60) | EPHX1TAS1R3TAS1R1TAS1R2SMN1; SMN2 | |
| SCHEMBL16204597 | 0.77 | EPHX1 (0.60) | EPHX1TAS1R3TAS1R1TAS1R2SMN1; SMN2 | |
| SCHEMBL13649856 | 0.77 | EPHX1 (0.60) | EPHX1TAS1R3TAS1R1TAS1R2SMN1; SMN2 | |
| SCHEMBL21512228 | 0.77 | EPHX1 (0.50) | EPHX1TAS1R3TAS1R1TAS1R2SMN1; SMN2 | |
| SCHEMBL22420112 | 0.77 | EPHX1 (0.46) | EPHX1TAS1R3TAS1R1TAS1R2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021055637-A1 | COMPOUNDS AND USES THEREOF | PANO THERAPEUTICS, INC. (US) | 2021-03-25 | — | — | WO | disclosed |
| WO-2018011160-A1 | 6,7-DIHYDRO-4H-PYRAZOLO[1,5-A]PYRAZINE COMPOUNDS FOR THE TREATMENT OF INFECTIOUS DISEASES | F. HOFFMANN-LA ROCHE AG (CH) | 2018-01-18 | — | — | WO | disclosed |