SCHEMBL9505661

SCHEMBL9505661

C=C(C)C(=O)NC1CCCCC1C

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.53
USP2 O75604 1/20 0.50
POLB P06746 1/20 0.49
TAS1R3 Q7RTX0 10/20 0.47
TAS1R1 Q7RTX1 9/20 0.47
TAS1R2 Q8TE23 7/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
ALDH1A1 P00352 2/20 0.42
MLYCD O95822 1/20 0.42
MAPT P10636 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9578877 0.81 CNR2 (0.36) EPHX1USP2POLBSMN1; SMN2ALDH1A1
SCHEMBL13649856 0.79 EPHX1 (0.60) EPHX1USP2POLBTAS1R3TAS1R1
SCHEMBL16204597 0.79 EPHX1 (0.60) EPHX1USP2POLBTAS1R3TAS1R1
SCHEMBL10331369 0.79 EPHX1 (0.60) EPHX1USP2POLBTAS1R3TAS1R1
SCHEMBL23772463 0.79 EPHX1 (0.60) EPHX1USP2POLBTAS1R3TAS1R1
SCHEMBL23772197 0.79 EPHX1 (0.60) EPHX1USP2POLBTAS1R3TAS1R1
SCHEMBL19781198 0.79 EPHX1 (0.50) EPHX1USP2POLBTAS1R3TAS1R1
SCHEMBL13191370 0.79 EPHX1 (0.60) EPHX1USP2POLBTAS1R3TAS1R1
SCHEMBL20662821 0.79 EPHX1 (0.51) EPHX1USP2POLBTAS1R3TAS1R1
SCHEMBL10254915 0.79 PSEN1 (0.40) USP2POLBSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0326938-B1 Impact-modified polycarbonate ROEHM GMBH (DE) 1993-12-22 EP disclosed
EP-0372213-B1 PROTECTIVE METHYCRYLATE LAYER FOR POLYCARBONATE, CONTAINING A UV ABSORBER RÖHM GMBH (DE) 1993-05-19 EP disclosed
EP-0368094-B1 IMPACT-RESISTANT PROTECTION METHACRYLATE LAYER CONTAINING A UV ABSORBER FOR POLYCARBONATE RÖHM GMBH (DE) 1992-05-06 EP disclosed
EP-0262502-B1 COMPATIBLE MIXTURES FROM POLYCARBONATE AND METHYLMETHACRYLATE COPOLYMERS RÖHM GMBH (DE) 1992-01-02 EP disclosed
US-5063112-A IMPACT-RESISTANT METHACRYLATE PROTECTIVE LAYER FOR POLYCARBONATE, CONTAINING UV ABSORBER ROHM GMBH CHEMISCHE FABRIK (DE) 1991-11-05 US disclosed
US-5061558-A METHACRYLATE PROTECTIVE COATING CONTAINING A UV-ABSORBER FOR POLYCARBONATE ROHM GMBH CHEMISCHE FABRIK (DE) 1991-10-29 US disclosed
US-4997883-A Methyl methacrylate copolymer ROHM GMBH CHEMISCHE FABRIK (DE) 1991-03-05 US disclosed
EP-0372213-A1 Protective methycrylate layer for polycarbonate, containing a UV absorber RÖHM GMBH (DE) 1990-06-13 EP disclosed
EP-0326938-A2 Impact-modified polycarbonate RÖHM GMBH (DE) 1989-08-09 EP disclosed
US-4749749-A TRANSPARENT THERMOPLASTIC BLEND; RING-SUBSTITUTED (METH)ACRYLAMIDE MONOMERS ROHM GMBH CHEMISCHE FABRIK (DE) 1988-06-07 US disclosed
EP-0262502-A2 Compatible mixtures from polycarbonate and methylmethacrylate copolymers Röhm GmbH (DE) 1988-04-06 EP disclosed