Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 2/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.40 |
| ▸ | NPY4R | P50391 | 2/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23286123 | 0.92 | CALCRL (0.52) | CALCRLGRIA1ITGB1ITGA5HDAC8 | |
| SCHEMBL16273801 | 0.89 | NPY4R (0.52) | CALCRLITGB1ITGA5NPY4RNPY1R | |
| SCHEMBL28474284 | 0.89 | NPY4R (0.52) | CALCRLITGB1ITGA5NPY4RNPY1R | |
| SCHEMBL27058431 | 0.84 | CALCRL (0.55) | CALCRLNPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL5549711 | 0.82 | SIRT2 (0.40) | CALCRLAKT1 | |
| SCHEMBL5549718 | 0.82 | SIRT2 (0.40) | CALCRLAKT1 | |
| SCHEMBL5549713 | 0.82 | SIRT2 (0.40) | CALCRLAKT1 | |
| SCHEMBL12972291 | 0.82 | ITGB1 (0.46) | CALCRLAKT1ITGB1ITGA5HDAC8 | |
| SCHEMBL23456780 | 0.81 | HDAC8 (0.48) | AKT1ITGB1HDAC8HDAC3HDAC1 | |
| SCHEMBL23456781 | 0.81 | HDAC8 (0.48) | AKT1ITGB1HDAC8HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10570192-B2 | Anti-wall teichoic antibodies and conjugates | GENENTECH, INC. (US) | 2020-02-25 | — | — | US | disclosed |
| US-20180016325-A1 | ANTI-WALL TEICHOIC ANTIBODIES AND CONJUGATES | GENENTECH, INC. (US) | 2018-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10570192-B2 | Anti-wall teichoic antibodies and conjugates | STT3A, STT3B, DDOST | CALCRL 4321/4885GRIA1 1669/4885AKT1 4718/4885 |
| US-20180016325-A1 | ANTI-WALL TEICHOIC ANTIBODIES AND CONJUGATES | STT3A, STT3B, DDOST | CALCRL 4321/4885GRIA1 1669/4885AKT1 4718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.