STT3B

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B · Q8TCJ2 · STT3B on Sugi Atlas →

237 patent compounds predicted against STT3B, 125 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL25725788 SCHEMBL25725788 1.00 1/20
SCHEMBL25726108 SCHEMBL25726108 1.00 1/20
SCHEMBL25726112 SCHEMBL25726112 1.00 1/20
SCHEMBL25726328 SCHEMBL25726328 0.85 1/20
SCHEMBL25733879 SCHEMBL25733879 0.85 1/20
SCHEMBL25726322 SCHEMBL25726322 0.82 1/20
SCHEMBL25726324 SCHEMBL25726324 0.82 1/20
SCHEMBL25725970 SCHEMBL25725970 0.78 1/20
SCHEMBL25726199 SCHEMBL25726199 0.78 1/20
SCHEMBL25726040 SCHEMBL25726040 0.74 1/20
SCHEMBL25733881 SCHEMBL25733881 0.74 1/20
SCHEMBL25733944 SCHEMBL25733944 0.73 1/20
SCHEMBL25726323 SCHEMBL25726323 0.73 1/20
SCHEMBL25726233 SCHEMBL25726233 0.72 1/20
SCHEMBL25726277 SCHEMBL25726277 0.72 1/20
SCHEMBL25725787 SCHEMBL25725787 0.72 1/20
SCHEMBL25726116 SCHEMBL25726116 0.72 1/20
SCHEMBL25726119 SCHEMBL25726119 0.72 1/20
SCHEMBL25733932 SCHEMBL25733932 0.72 1/20
SCHEMBL25726372 SCHEMBL25726372 0.71 1/20

Clinical trials — most relevant to STT3B by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Vaccine Treatment for Advanced Non-Small Cell Lung Cancer PHASE1/PHASE2COMPLETED
The Effect of Triheptanoin on Fatty Acid Oxidation and Exercise Tolerance in Patients With Glycogenoses PHASE2COMPLETED
GD2/CD70 Bi-specific CAR-T Cell Therapy PHASE1/PHASE2RECRUITING
Study of Safety, Tolerability and Efficacy of PBGM01 in Pediatric Participants With GM1 Gangliosidosis PHASE1/PHASE2ACTIVE_NOT_RECRUITING
A Phase 1/2 Study of Intravenous Gene Transfer With an AAV9 Vector Expressing Human Beta-galactosidase in Type I and Type II GM1 Gangliosidosis PHASE1/PHASE2RECRUITING
24-Week Study to Assess the PD, Safety, Tolerability, and PK of GLM101 in Participants With PMM2-CDG PHASE2COMPLETED
GD2/CD56 Bi-specific CAR-T Cell Therapy PHASE1/PHASE2RECRUITING
A Phase 1 Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ManNAc in Subjects With Primary Podocyte Diseases PHASE1COMPLETED
Vaccine Therapy Plus Biological Therapy in Treating Patients With Prostate Cancer PHASE1COMPLETED
Intravenous Immune Globulin to Treat Hereditary Inclusion Body Myopathy PHASE1COMPLETED
Glycosylation in Patients With Galactosaemia nanCOMPLETED
A Retrospective Study to Identify New Omics Biomarkers of Chronic/Persistent Low Back Pain nanCOMPLETED
Incidence and Consequences of Disorders of Glycosylation in Patients With Conotruncal and Septal Heart Defects nanUNKNOWN
The Natural History of Alpha-Mannosidosis nanCOMPLETED
Biomarker for Mannosidosis Disease (BioMannosidosis) nanWITHDRAWN
Glycoprotein and Glycan in Tissue and Blood Samples of Patients With Stage IB-IVA Cervical Cancer Undergoing Surgery to Remove Pelvic and Abdominal Lymph Nodes nanCOMPLETED
Biomarker for Hurler Disease (BioHurler) nanWITHDRAWN
Canadian Fabry Disease Initiative (CFDI) National Registry nanRECRUITING
A Post-Authorisation Safety Study Patient Registry of Patients With Neuroblastoma Being Treated With Dinutuximab Beta nanRECRUITING
Characterizing the Retinal Microvasculature in Patients with Fabry Disease: a Prospective Observational Study nanRECRUITING
Biomarker for Mucolipidosis Disorder Type I, II, III, IV (BioML) nanWITHDRAWN
Glycoprotein in Immunotherapy Response and Efficacy Prediction of Lung Cancer nanRECRUITING
Dietary Monosaccharide Supplementation in Patients With Congenital Disorders of Glycosylation nanCOMPLETED
Evaluation of Gastrointestinal Symptoms Following Chilean Native Beans Consumption nanUNKNOWN
Glycan Attachment Specificity, Toward ROtavirus Vaccine IMprovement GASTROVIMc (Clinical Investigation) nanCOMPLETED
Using D-Galactose as a Food Supplement in Congenital Disorders of Glycosylation nanCOMPLETED
The Natural History of Sialidosis Type I nanRECRUITING
Lyso-Gb1 as a Long-term Prognostic Biomarker in Gaucher Disease nanCOMPLETED
Evaluation of Blood and Cardiac Protein O-GlcNAcylation Levels in Cardiac Surgery in Children nanRECRUITING
Biomarker for Gangliosidosis: BioGM1/BioGM2 (BioGM1/GM2) nanWITHDRAWN

Related proteins — ESM-2 sequence neighbours (a STT3B binder may also engage these)

ProteinNameSimilarity
Q3TDQ1 1.000 Q3TDQ1 →
E2RG47 0.999 E2RG47 →
Q7XQ88 0.997 Q7XQ88 →
O94335 0.995 O94335 →
Q6F2Z1 0.994 Q6F2Z1 →
Q5RCE2 0.993 Q5RCE2 →
STT3A Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A 0.993 landscape →
P39007 0.993 P39007 →
F1PJP5 0.993 F1PJP5 →
Q93ZY3 0.993 Q93ZY3 →
Q2KJI2 0.992 Q2KJI2 →
A8Y3M2 0.992 A8Y3M2 →
P46978 0.992 P46978 →
Q7Z388 0.990 Q7Z388 →
O97681 0.989 O97681 →
D4AD75 0.989 D4AD75 →
Q9HDZ2 0.989 Q9HDZ2 →
P25618 0.988 P25618 →
P34413 0.988 P34413 →
Q29IL2 0.988 Q29IL2 →
P12683 0.988 P12683 →
O93869 0.988 O93869 →
P23337 0.987 P23337 →
Q93380 0.987 Q93380 →
Q54E04 0.987 Q54E04 →
P0CW70 0.987 P0CW70 →
Q9Z1E4 0.987 Q9Z1E4 →
P46975 0.987 P46975 →
Q9UTI7 0.987 Q9UTI7 →
D4A2Z8 0.987 D4A2Z8 →