Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 1.00 |
| ▸ | PPARG | P37231 | 3/20 | 0.74 |
| ▸ | PPARA | Q07869 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.61 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | PLK1 | P53350 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | ACACB | O00763 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19781301 | 1.00 | NPSR1 (1.00) | NPSR1PPARGPPARAKMT2AMEN1 | |
| SCHEMBL9830234 | 0.89 | PPARG (0.92) | NPSR1PPARGPPARAKMT2AMEN1 | |
| SCHEMBL19781327 | 0.89 | PPARG (0.83) | NPSR1PPARGPPARAKMT2AMEN1 | |
| SCHEMBL19781326 | 0.89 | PPARG (0.83) | NPSR1PPARGPPARAKMT2AMEN1 | |
| SCHEMBL9830231 | 0.89 | PPARG (0.92) | NPSR1PPARGPPARAKMT2AMEN1 | |
| SCHEMBL3082191 | 0.88 | NPSR1 (0.77) | NPSR1PPARGPPARARAB9AGAA | |
| SCHEMBL19781325 | 0.85 | PPARG (1.00) | NPSR1PPARGPPARAPLK1 | |
| SCHEMBL19780924 | 0.85 | PPARG (1.00) | NPSR1PPARGPPARAPLK1 | |
| SCHEMBL10294829 | 0.84 | NPSR1 (0.72) | NPSR1KMT2AMEN1TAS1R3TAS1R1 | |
| SCHEMBL3096415 | 0.83 | NPSR1 (0.69) | NPSR1PPARGPPARAKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018011230-A1 | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA AGONISTS, METHOD OF PREPARATION AND USES THEREOF | UNIVERSITE D'AIX-MARSEILLE (FR) | 2018-01-18 | — | — | WO | disclosed |