Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.92 |
| ▸ | PPARA | Q07869 | 1/20 | 0.92 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.80 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.53 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PLK1 | P53350 | 1/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830234 | 1.00 | PPARG (0.92) | PPARGPPARANPSR1CA2CA1 | |
| SCHEMBL19780924 | 0.96 | PPARG (1.00) | PPARGPPARANPSR1TP53TSHR | |
| SCHEMBL19781325 | 0.96 | PPARG (1.00) | PPARGPPARANPSR1TP53TSHR | |
| SCHEMBL19781326 | 0.94 | PPARG (0.83) | PPARGPPARANPSR1CA2CA1 | |
| SCHEMBL19781327 | 0.94 | PPARG (0.83) | PPARGPPARANPSR1CA2CA1 | |
| SCHEMBL19781301 | 0.89 | NPSR1 (1.00) | PPARGPPARANPSR1CA2CA1 | |
| SCHEMBL19781302 | 0.89 | NPSR1 (1.00) | PPARGPPARANPSR1CA2CA1 | |
| SCHEMBL19780913 | 0.84 | PPARG (0.80) | PPARGPPARANPSR1TAS1R3TAS1R1 | |
| SCHEMBL19781331 | 0.84 | PPARG (0.80) | PPARGPPARANPSR1TAS1R3TAS1R1 | |
| SCHEMBL19781332 | 0.84 | PPARG (0.80) | PPARGPPARANPSR1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |