Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.74 |
| ▸ | PPARA | Q07869 | 1/20 | 0.74 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | ASAH2 | Q9NR71 | 2/20 | 0.59 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.58 |
| ▸ | RARB | P10826 | 3/20 | 0.56 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.54 |
| ▸ | PLK1 | P53350 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13753454 | 0.99 | PPARG (0.72) | PPARGPPARATP53TSHRASAH2 | |
| SCHEMBL19781325 | 0.85 | PPARG (1.00) | PPARGPPARATP53TSHRPLA2G4B | |
| SCHEMBL19780924 | 0.85 | PPARG (1.00) | PPARGPPARATP53TSHRPLA2G4B | |
| SCHEMBL19780913 | 0.84 | PPARG (0.80) | PPARGPPARATP53TSHRASAH2 | |
| SCHEMBL19780916 | 0.84 | PPARG (0.80) | PPARGPPARATP53TSHRASAH2 | |
| SCHEMBL19781331 | 0.84 | PPARG (0.80) | PPARGPPARATP53TSHRASAH2 | |
| SCHEMBL19781332 | 0.84 | PPARG (0.80) | PPARGPPARATP53TSHRASAH2 | |
| SCHEMBL19781324 | 0.83 | PPARG (1.00) | PPARGPPARATP53TSHRPLA2G4B | |
| SCHEMBL19781328 | 0.83 | PPARG (1.00) | PPARGPPARATP53TSHRPLA2G4B | |
| SCHEMBL12638345 | 0.83 | PPARG (0.66) | PPARGPPARATP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018011230-A1 | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA AGONISTS, METHOD OF PREPARATION AND USES THEREOF | UNIVERSITE D'AIX-MARSEILLE (FR) | 2018-01-18 | — | — | WO | disclosed |