Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 1.00 |
| ▸ | PPARA | Q07869 | 1/20 | 0.78 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.52 |
| ▸ | TAOK3 | Q9H2K8 | 2/20 | 0.52 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19781324 | 1.00 | PPARG (1.00) | PPARGPPARANPSR1TP53TSHR | |
| SCHEMBL19780924 | 0.88 | PPARG (1.00) | PPARGPPARANPSR1TP53TSHR | |
| SCHEMBL19781325 | 0.88 | PPARG (1.00) | PPARGPPARANPSR1TP53TSHR | |
| SCHEMBL19780916 | 0.86 | PPARG (0.80) | PPARGPPARANPSR1TP53TSHR | |
| SCHEMBL13366238 | 0.86 | PPARG (0.76) | PPARGPPARANPSR1MMP1 | |
| SCHEMBL19781331 | 0.86 | PPARG (0.80) | PPARGPPARANPSR1TP53TSHR | |
| SCHEMBL19780913 | 0.86 | PPARG (0.80) | PPARGPPARANPSR1TP53TSHR | |
| SCHEMBL19781332 | 0.86 | PPARG (0.80) | PPARGPPARANPSR1TP53TSHR | |
| SCHEMBL9830234 | 0.83 | PPARG (0.92) | PPARGPPARANPSR1TP53TSHR | |
| SCHEMBL9830231 | 0.83 | PPARG (0.92) | PPARGPPARANPSR1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018011230-A1 | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA AGONISTS, METHOD OF PREPARATION AND USES THEREOF | UNIVERSITE D'AIX-MARSEILLE (FR) | 2018-01-18 | — | — | WO | disclosed |