Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.39 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SCN4A | P35499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20621316 | 0.88 | TSHR (0.46) | TSHRSCN8ASSTR4ARKDM4E | |
| SCHEMBL23269915 | 0.86 | PTPN1 (0.49) | TSHRSCN8ASSTR4PTPN1AR | |
| SCHEMBL6389982 | 0.84 | SSTR2 (0.39) | SSTR2AREGFRERBB2GAA | |
| SCHEMBL19768976 | 0.82 | NAMPT (0.47) | SSTR2ARKDM4EALDH1A1EGFR | |
| SCHEMBL22096809 | 0.82 | SSTR2 (0.38) | TSHRSSTR2AREGFRERBB2 | |
| SCHEMBL19779792 | 0.79 | NAMPT (0.38) | SSTR2AREGFRERBB2 | |
| SCHEMBL23491315 | 0.78 | TSHR (0.48) | TSHRSCN8ASSTR4ARGCK | |
| SCHEMBL7466903 | 0.77 | AR (0.46) | TSHRARKDM4EALDH1A1HPGD | |
| SCHEMBL23817494 | 0.76 | TSHR (0.47) | TSHRSCN8ASSTR4ARKDM4E | |
| SCHEMBL16952724 | 0.76 | TSHR (0.50) | TSHRSCN8ASSTR4ARALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013676-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2018-01-18 | — | — | WO | disclosed |