Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23269569 | 1.00 | EPHX1 (0.38) | EPHX1SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL23269572 | 0.83 | GABRR1 (0.44) | SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL19781544 | 0.83 | GABRR1 (0.44) | SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL23269565 | 0.83 | GABRR1 (0.44) | SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL14311906 | 0.82 | SLC6A2 (0.36) | EPHX1SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL23269930 | 0.80 | EPHX1 (0.37) | EPHX1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL14311983 | 0.80 | ALDH1A1 (0.38) | EPHX1SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL23269728 | 0.79 | SLC6A2 (0.35) | SLC6A2SLC6A4SLC6A3ALDH1A1NCF1 | |
| SCHEMBL23269566 | 0.79 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23269568 | 0.79 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021076448-A1 | SOMATOSTATIN MODULATORS FOR TREATING PITUITARY ADENOMAS | Crinetics Pharmaceuticals, Inc. (US) | 2021-04-22 | — | — | WO | disclosed |
| WO-2018013676-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2018-01-18 | — | — | WO | disclosed |