Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1977033 | 0.89 | ALDH1A1 (0.46) | ALDH1A1GAAHTTTHRBL3MBTL1 | |
| SCHEMBL1441301 | 0.89 | ALDH1A1 (0.46) | ALDH1A1GAAHTTTHRBL3MBTL1 | |
| SCHEMBL1440524 | 0.88 | ALDH1A1 (0.48) | ALDH1A1GAAHTTTHRBL3MBTL1 | |
| SCHEMBL1440527 | 0.88 | ALDH1A1 (0.48) | ALDH1A1GAAHTTTHRBL3MBTL1 | |
| SCHEMBL1981365 | 0.86 | ALDH1A1 (0.51) | ALDH1A1GAAHTTTHRBL3MBTL1 | |
| SCHEMBL1977963 | 0.85 | ALDH1A1 (0.48) | ALDH1A1GAAHTTTHRBL3MBTL1 | |
| SCHEMBL1977965 | 0.85 | ALDH1A1 (0.48) | ALDH1A1GAAHTTTHRBL3MBTL1 | |
| SCHEMBL6870240 | 0.82 | ALDH1A1 (0.43) | ALDH1A1GAAHTTTHRBL3MBTL1 | |
| SCHEMBL2592261 | 0.81 | ALDH1A1 (0.38) | ALDH1A1GAAHTTTHRBL3MBTL1 | |
| SCHEMBL2592263 | 0.81 | ALDH1A1 (0.38) | ALDH1A1GAAHTTTHRBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509966-A1 | AMINO OXAZINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011070029-A1 | AMINO OXAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2011-06-16 | — | — | WO | disclosed |