Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1752393 | 0.80 | TSHR (0.37) | TSHRHTTHSD17B10MGAMGAA | |
| SCHEMBL28289211 | 0.78 | TSHR (0.36) | TSHRHTTHSD17B10MGAMGAA | |
| SCHEMBL22113432 | 0.73 | TSHR (0.42) | TSHRHTTHSD17B10MGAMGAA | |
| SCHEMBL20382939 | 0.71 | — | — | |
| SCHEMBL19233797 | 0.71 | TSHR (0.40) | TSHRHTTHSD17B10MGAMGAA | |
| SCHEMBL22649369 | 0.69 | TSHR (0.39) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL27392936 | 0.68 | TSHR (0.37) | TSHRHTTHSD17B10MGAMGAA | |
| SCHEMBL23175627 | 0.68 | GAA (0.45) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL5077875 | 0.67 | TSHR (0.50) | TSHRHTTHSD17B10MGAMGAA | |
| SCHEMBL5081302 | 0.67 | TSHR (0.50) | TSHRHTTHSD17B10MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018011160-A1 | 6,7-DIHYDRO-4H-PYRAZOLO[1,5-A]PYRAZINE COMPOUNDS FOR THE TREATMENT OF INFECTIOUS DISEASES | F. HOFFMANN-LA ROCHE AG (CH) | 2018-01-18 | — | — | WO | disclosed |