Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MGAM | O43451 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | SI | P14410 | 2/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23175627 | 0.86 | GAA (0.45) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL3249360 | 0.83 | ALDH1A1 (0.36) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL14192720 | 0.83 | KMT2A (0.34) | TSHRSMN1; SMN2KMT2AANPEPALDH1A1 | |
| SCHEMBL28289211 | 0.82 | TSHR (0.36) | TSHRHTTHSD17B10MGAMGAA | |
| SCHEMBL11670845 | 0.80 | CA1 (0.38) | TSHRSMN1; SMN2KMT2AANPEPALDH1A1 | |
| SCHEMBL13548729 | 0.80 | ALDH1A1 (0.33) | TSHRSMN1; SMN2ANPEPALDH1A1 | |
| SCHEMBL8685566 | 0.80 | TSHR (0.44) | TSHRHTTHSD17B10MGAMGAA | |
| SCHEMBL16006403 | 0.80 | TDP1 (0.33) | SMN1; SMN2ANPEPCA1CA2 | |
| SCHEMBL19781690 | 0.80 | TSHR (0.34) | TSHRHTTHSD17B10MGAMGAA | |
| SCHEMBL13315130 | 0.79 | CA1 (0.32) | SMN1; SMN2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4442298-A | Chemical synthesis of ethylene/maleic anhydride dimer with phenylethyl end group | MONSANTO COMPANY (US) | 1984-04-10 | — | — | US | claimed |
| WO-2025059469-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS AS AKT INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |
| CN-113174002-B | Ultrahigh molecular weight polyethylene catalyst, and preparation method and application thereof | 上海化工研究院有限公司 | 2023-04-07 | — | — | CN | disclosed |
| US-11584748-B2 | Spirocyclic compounds | C4 THERAPEUTICS, INC. (US) | 2023-02-21 | — | — | US | disclosed |
| US-11168086-B2 | Methods of synthesizing pyrazine compounds | HOFFMANN-LA ROCHE INC. (US) | 2021-11-09 | — | — | US | disclosed |
| US-11168086-B2 | Methods of synthesizing pyrazine compounds | HOFFMANN-LA ROCHE INC. (US) | 2021-11-09 | — | — | US | disclosed |
| CN-113174002-A | Ultrahigh molecular weight polyethylene catalyst, and preparation method and application thereof | 上海化工研究院有限公司 | 2021-07-27 | — | — | CN | disclosed |
| US-20210032245-A1 | SPIROCYCLIC COMPOUNDS | C4 THERAPEUTICS, INC. (US) | 2021-02-04 | — | — | US | disclosed |
| CN-112312904-A | Spiro compounds | C4医药公司 | 2021-02-02 | — | — | CN | disclosed |
| CN-107207515-B | Pyrazine compounds for the treatment of infectious diseases | 豪夫迈·罗氏有限公司 | 2019-05-28 | — | — | CN | disclosed |
| US-4521344-A | Cyano-dicarboxylate | MONSANTO COMPANY (US) | 1985-06-04 | — | — | US | disclosed |
| US-4521344-A | Cyano-dicarboxylate | MONSANTO COMPANY (US) | 1985-06-04 | — | — | US | disclosed |
| US-4514340-A | Cyano-polycarboxylates | MONSANTO COMPANY (US) | 1985-04-30 | — | — | US | disclosed |
| US-4514340-A | Cyano-polycarboxylates | MONSANTO COMPANY (US) | 1985-04-30 | — | — | US | disclosed |
| US-4442298-A | Chemical synthesis of ethylene/maleic anhydride dimer with phenylethyl end group | MONSANTO COMPANY (US) | 1984-04-10 | — | — | US | disclosed |
| US-4442298-A | Chemical synthesis of ethylene/maleic anhydride dimer with phenylethyl end group | MONSANTO COMPANY (US) | 1984-04-10 | — | — | US | disclosed |
| US-4428887-A | Method of producing mono-substituted terminal diesters | MONSANTO COMPANY (US) | 1984-01-31 | — | — | US | disclosed |
| EP-0028430-B1 | A PROCESS FOR THE ELECTROREDUCTIVE PREPARATION OF ORGANIC COMPOUNDS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1984-01-18 | — | — | EP | disclosed |
| EP-0028430-A1 | A process for the electroreductive preparation of organic compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1981-05-13 | — | — | EP | disclosed |
| US-4028201-A | Electrolytic monocarboxylation of activated olefins | MONSANTO COMPANY (US) | 1977-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11168086-B2 | Methods of synthesizing pyrazine compounds | CYP3A5, HAVCR2, HCCS | TSHR 245/4885HTT 2541/4885HSD17B10 1085/4885 |
| US-20210032245-A1 | SPIROCYCLIC COMPOUNDS | CRBN, RBX1, XIAP | TSHR 3397/4885HTT 1685/4885HSD17B10 1926/4885 |
| US-11584748-B2 | Spirocyclic compounds | CRBN, RBX1, XIAP | TSHR 3397/4885HTT 1685/4885HSD17B10 1926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.