SCHEMBL19782438

SCHEMBL19782438

C[C@@H](COC(=O)Nc1cnc(OCCO)nc1)Oc1cc2sc(Cl)nc2cc1F

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 18/20 0.47
P2RX3 P56373 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21395332 0.87 F2RL3 (0.48) F2RL3P2RX3
SCHEMBL21395896 0.82 F2RL3 (0.72) F2RL3
SCHEMBL21396070 0.82 F2RL3 (0.64) F2RL3
SCHEMBL21395994 0.82 F2RL3 (0.72) F2RL3
SCHEMBL21395701 0.80 F2RL3 (0.72) F2RL3
SCHEMBL21395488 0.79 F2RL3 (0.72) F2RL3
SCHEMBL21942183 0.78 F2RL3 (0.68) F2RL3
SCHEMBL19784735 0.78 F2RL3 (0.68) F2RL3
SCHEMBL19784736 0.78 F2RL3 (0.68) F2RL3
SCHEMBL19782442 0.78 ACACB (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018013774-A1 BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2018-01-18 WO disclosed