Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.34 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13235872 | 0.77 | NAPRT (0.44) | DGAT1NAPRTALDH1A1SMN1; SMN2POLB | |
| SCHEMBL19525331 | 0.77 | SMN1; SMN2 (0.40) | DGAT1NAPRTSMN1; SMN2POLBCYP3A4 | |
| SCHEMBL1963300 | 0.77 | BRD4 (0.50) | SMN1; SMN2POLBMEN1KMT2ARAB9A | |
| SCHEMBL19752631 | 0.77 | SMN1; SMN2 (0.40) | DGAT1NAPRTSMN1; SMN2POLBCYP3A4 | |
| SCHEMBL27478228 | 0.75 | NAPRT (0.46) | DGAT1NAPRTALDH1A1SMN1; SMN2POLB | |
| SCHEMBL31420077 | 0.74 | NAPRT (0.48) | NAPRTSMN1; SMN2POLBPKMLMNA | |
| SCHEMBL7783101 | 0.74 | NAPRT (0.44) | DGAT1NAPRTALDH1A1SMN1; SMN2POLB | |
| SCHEMBL1747676 | 0.74 | NAPRT (0.48) | NAPRTSMN1; SMN2POLBPKMLMNA | |
| SCHEMBL11446345 | 0.72 | BRD4 (0.46) | ALDH1A1SMN1; SMN2LMNASLC6A4SLC6A3 | |
| SCHEMBL594060 | 0.72 | CYP3A4 (0.42) | DGAT1NAPRTALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011069955-A1 | SULFONIMIDAMIDE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2011-06-16 | — | — | WO | disclosed |
| WO-2011069955-A1 | SULFONIMIDAMIDE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2011-06-16 | — | — | WO | disclosed |