Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 14/20 | 0.48 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19783108 | 0.93 | DHODH (0.56) | DHODHP2RY1SYKMEN1MAPT | |
| SCHEMBL19782988 | 0.81 | CDC7 (0.46) | DHODHMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL19782989 | 0.80 | DHODH (0.43) | DHODHMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL15993448 | 0.79 | DHODH (0.53) | DHODHMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL29078713 | 0.79 | DHODH (0.56) | DHODHP2RY1MEN1MAPTKMT2A | |
| SCHEMBL19782993 | 0.77 | DHODH (0.47) | DHODHMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL15993345 | 0.76 | DHODH (0.58) | DHODHMEN1MAPTKMT2A | |
| SCHEMBL15993447 | 0.72 | DHODH (0.54) | DHODHMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL21245761 | 0.72 | CDC7 (0.56) | DHODHMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL15993418 | 0.72 | DHODH (0.53) | DHODHMEN1MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013508-A1 | SUBSTITUTED AMINOTHIAZOLES | BARUCH S. BLUMBERG INSTITUTE (US) | 2018-01-18 | — | — | WO | disclosed |