Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 14/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19783106 | 0.92 | DHODH (0.53) | DHODHMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL19782988 | 0.84 | CDC7 (0.46) | DHODHMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL19782394 | 0.84 | DHODH (0.38) | DHODHMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL19782390 | 0.83 | DHODH (0.36) | DHODHMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL19782993 | 0.81 | DHODH (0.47) | DHODHMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL19782880 | 0.80 | DHODH (0.48) | DHODHMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL15993345 | 0.80 | DHODH (0.58) | DHODHMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21245761 | 0.76 | CDC7 (0.56) | DHODHMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL15993447 | 0.76 | DHODH (0.54) | DHODHMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL15993448 | 0.75 | DHODH (0.53) | DHODHMEN1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013508-A1 | SUBSTITUTED AMINOTHIAZOLES | BARUCH S. BLUMBERG INSTITUTE (US) | 2018-01-18 | — | — | WO | disclosed |