Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19782935 | 0.81 | KMT2A (0.55) | MEN1KMT2AMAPK1ALDH1A1USP2 | |
| SCHEMBL15968855 | 0.77 | MEN1 (0.72) | MEN1KMT2AMAPK1ALDH1A1USP2 | |
| SCHEMBL3450804 | 0.74 | MAPK1 (0.55) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL15988936 | 0.73 | TSHR (0.73) | MEN1KMT2ATSHRMAPK1L3MBTL1 | |
| SCHEMBL10841330 | 0.73 | ALDH1A1 (0.64) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL8785393 | 0.73 | CYP1A2 (0.67) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL15595466 | 0.71 | TSHR (0.69) | MEN1KMT2ATSHRMAPK1L3MBTL1 | |
| SCHEMBL6276143 | 0.71 | ALDH1A1 (0.67) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL1015707 | 0.71 | TSHR (0.73) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL17967103 | 0.71 | MAPK1 (0.67) | MEN1KMT2ATSHRMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018011376-A1 | PYRIMIDINONE DERIVATIVES AND USES THEREOF TO NEUTRALIZE THE BIOLOGICAL ACTIVITY OF CHEMOKINES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS - (FR) | 2018-01-18 | — | — | WO | disclosed |