SCHEMBL19782945

SCHEMBL19782945

C=Cc1cc(-c2nc3c(C)cc(OCCNSc4ccc(F)cc4)cc3s2)c2ncc(COC)nc2c1

nearest known ligand 0.52

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 9/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19783405 0.87 F2RL3 (0.56) F2RL3
SCHEMBL19783311 0.85 F2RL3 (0.53) F2RL3
SCHEMBL30187703 0.85 F2RL3 (0.70) F2RL3
SCHEMBL21379560 0.85 F2RL3 (0.70) F2RL3
SCHEMBL19783423 0.82 F2RL3 (0.54) F2RL3
SCHEMBL30187739 0.77 F2RL3 (0.70) F2RL3
SCHEMBL19783318 0.77 F2RL3 (0.70) F2RL3
SCHEMBL21379388 0.76 F2RL3 (0.76) F2RL3
SCHEMBL30187636 0.75 F2RL3 (0.85) F2RL3
SCHEMBL19782546 0.75 F2RL3 (0.85) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018013774-A1 BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2018-01-18 WO disclosed