Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 10/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19783405 | 0.94 | F2RL3 (0.56) | F2RL3NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL30189667 | 0.86 | F2RL3 (0.70) | F2RL3MAPT | |
| SCHEMBL19783301 | 0.86 | F2RL3 (0.70) | F2RL3MAPT | |
| SCHEMBL19782945 | 0.85 | F2RL3 (0.52) | F2RL3 | |
| SCHEMBL19783423 | 0.83 | F2RL3 (0.54) | F2RL3 | |
| SCHEMBL28941163 | 0.82 | F2RL3 (0.50) | F2RL3MAPK14 | |
| SCHEMBL19783404 | 0.81 | F2RL3 (0.74) | F2RL3MAPT | |
| SCHEMBL30189686 | 0.81 | F2RL3 (0.74) | F2RL3MAPT | |
| SCHEMBL21379615 | 0.80 | F2RL3 (0.70) | F2RL3MAPT | |
| SCHEMBL30189675 | 0.80 | F2RL3 (0.70) | F2RL3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013774-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-01-18 | — | — | WO | disclosed |