Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 4/20 | 0.36 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | ILK | Q13418 | 10/20 | 0.34 |
| ▸ | EGFR | P00533 | 3/20 | 0.32 |
| ▸ | ITK | Q08881 | 1/20 | 0.32 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19783337 | 0.84 | ILK (0.37) | STING1ACACBILKTRPV3 | |
| SCHEMBL21379450 | 0.82 | STING1 (0.36) | STING1ACACBILK | |
| SCHEMBL19783119 | 0.82 | STING1 (0.36) | STING1ACACBILK | |
| SCHEMBL21379409 | 0.78 | ACACB (0.40) | STING1ACACBILK | |
| SCHEMBL19783677 | 0.78 | ACACB (0.40) | STING1ACACBILK | |
| SCHEMBL19784621 | 0.76 | ILK (0.51) | STING1ILK | |
| SCHEMBL19782975 | 0.76 | PIK3CD (0.38) | ACACBILK | |
| SCHEMBL19783238 | 0.75 | — | — | |
| SCHEMBL21379671 | 0.74 | ACACB (0.42) | STING1ACACBILK | |
| SCHEMBL19783130 | 0.74 | ACACB (0.42) | STING1ACACBILK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013774-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-01-18 | — | — | WO | disclosed |