SCHEMBL19783124

SCHEMBL19783124

Cc1cc(-c2nc3cc(F)c(OCCO)nc3s2)c2ncc(OC(F)F)nc2c1

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 20/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30189958 0.91 F2RL3 (0.53) F2RL3
SCHEMBL19783683 0.91 F2RL3 (0.53) F2RL3
SCHEMBL19783767 0.89 F2RL3 (0.52) F2RL3
SCHEMBL21379417 0.89 F2RL3 (0.56) F2RL3
SCHEMBL30189549 0.89 F2RL3 (0.56) F2RL3
SCHEMBL21379418 0.89 F2RL3 (0.56) F2RL3
SCHEMBL21395682 0.86 F2RL3 (0.58) F2RL3
SCHEMBL30189699 0.86 F2RL3 (0.58) F2RL3
SCHEMBL19782272 0.84 F2RL3 (0.62) F2RL3
SCHEMBL21379405 0.80 F2RL3 (0.53) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018013774-A1 BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2018-01-18 WO disclosed