SCHEMBL19783767

SCHEMBL19783767

CCOc1cnc2c(-c3nc4cc(F)c(OCCO)nc4s3)cc(C)cc2n1

nearest known ligand 0.52

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 20/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19783683 0.93 F2RL3 (0.53) F2RL3
SCHEMBL30189958 0.93 F2RL3 (0.53) F2RL3
SCHEMBL19783124 0.89 F2RL3 (0.57) F2RL3
SCHEMBL21379447 0.88 F2RL3 (0.44) F2RL3
SCHEMBL19783713 0.88 F2RL3 (0.45) F2RL3
SCHEMBL30189766 0.87 F2RL3 (0.47) F2RL3
SCHEMBL21379316 0.87 F2RL3 (0.47) F2RL3
SCHEMBL19783766 0.87 F2RL3 (0.47) F2RL3
SCHEMBL23462960 0.86 F2RL3 (0.46) F2RL3
SCHEMBL21379690 0.85 F2RL3 (0.47) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018013774-A1 BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2018-01-18 WO disclosed