Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19782739 | 0.81 | F2RL3 (0.34) | — | |
| SCHEMBL19783267 | 0.79 | GLRA3 (0.47) | — | |
| SCHEMBL19783574 | 0.78 | F2RL3 (0.48) | — | |
| SCHEMBL22341973 | 0.74 | IKBKB (0.42) | IKBKB | |
| SCHEMBL19783579 | 0.72 | IKBKB (0.53) | IKBKB | |
| SCHEMBL30189687 | 0.72 | IKBKB (0.53) | IKBKB | |
| SCHEMBL30189966 | 0.69 | CA12 (0.40) | IKBKB | |
| SCHEMBL19783409 | 0.68 | IKBKB (0.43) | IKBKB | |
| SCHEMBL30189475 | 0.66 | RECQL (0.38) | IKBKB | |
| SCHEMBL19783074 | 0.66 | RECQL (0.38) | IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013774-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-01-18 | — | — | WO | disclosed |