Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.30 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21422301 | 0.87 | TLR8 (0.38) | TLR8CYP11B2CYP2A6EP300KAT2B | |
| SCHEMBL21422266 | 0.85 | ADORA2A (0.39) | TLR8CYP11B2CYP2A6POLBGRM1 | |
| SCHEMBL19783854 | 0.84 | TLR8 (0.38) | TLR8CYP11B2CYP2A6EP300KAT2B | |
| SCHEMBL19784106 | 0.81 | TLR8 (0.38) | TLR8CYP11B2CYP2A6EP300KAT2B | |
| SCHEMBL19783996 | 0.79 | TLR8 (0.36) | TLR8CYP2A6MTORHTTGAA | |
| SCHEMBL19784142 | 0.76 | TLR8 (0.35) | TLR8CYP11B2CYP2A6EP300KAT2B | |
| SCHEMBL21422265 | 0.74 | TLR8 (0.43) | TLR8CYP2A6HTTPOLBGAA | |
| SCHEMBL17803459 | 0.71 | CYP2A6 (0.40) | TLR8CYP11B2CYP2A6HTTGAA | |
| SCHEMBL17803445 | 0.71 | CYP2A6 (0.40) | TLR8CYP11B2CYP2A6EP300KAT2B | |
| SCHEMBL19342601 | 0.71 | CYP2A6 (0.43) | TLR8CYP11B2CYP2A6HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484877-B1 | BICYCLIC COMPOUNDS AS PEST CONTROLLERS | BAYER CROPSCIENCE AG (DE) | 2020-07-01 | — | — | EP | disclosed |
| WO-2018011111-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-01-18 | — | — | WO | disclosed |