Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | USP8 | P40818 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 2/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21422259 | 0.87 | ESR2 (0.39) | TLR8ESR2CYP2A6CYP11B2GRM1 | |
| SCHEMBL19783858 | 0.87 | TLR8 (0.45) | TLR8ESR2CYP2A6CYP11B2GRM1 | |
| SCHEMBL19784106 | 0.86 | TLR8 (0.38) | TLR8ESR2CYP2A6CYP11B2GRM1 | |
| SCHEMBL19783977 | 0.86 | ESR2 (0.41) | TLR8ESR2CYP2A6CYP11B2GRM1 | |
| SCHEMBL19783976 | 0.84 | ADORA2A (0.39) | TLR8ESR2CYP2A6CYP11B2GRM1 | |
| SCHEMBL19783274 | 0.84 | TLR8 (0.38) | TLR8CYP2A6CYP11B2GRM1EP300 | |
| SCHEMBL19783853 | 0.84 | CYP11B2 (0.37) | ESR2CYP11B2 | |
| SCHEMBL19784142 | 0.83 | TLR8 (0.35) | TLR8CYP2A6CYP11B2GRM1EP300 | |
| SCHEMBL19783867 | 0.82 | CYP11B2 (0.37) | TLR8ESR2CYP2A6CYP11B2GRM1 | |
| SCHEMBL19783974 | 0.82 | POLB (0.38) | TLR8ESR2CYP2A6CYP11B2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484877-B1 | BICYCLIC COMPOUNDS AS PEST CONTROLLERS | BAYER CROPSCIENCE AG (DE) | 2020-07-01 | — | — | EP | disclosed |
| WO-2018011111-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-01-18 | — | — | WO | disclosed |