Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 14/20 | 0.63 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21379424 | 0.92 | F2RL3 (0.70) | F2RL3BRD4L3MBTL1 | |
| SCHEMBL30187624 | 0.87 | F2RL3 (0.69) | F2RL3CYP3A4 | |
| SCHEMBL19782963 | 0.87 | F2RL3 (0.69) | F2RL3CYP3A4 | |
| SCHEMBL21379377 | 0.84 | F2RL3 (0.58) | F2RL3 | |
| SCHEMBL21379398 | 0.82 | F2RL3 (0.72) | F2RL3 | |
| SCHEMBL22342201 | 0.80 | F2RL3 (0.62) | F2RL3 | |
| SCHEMBL28941196 | 0.79 | F2RL3 (0.58) | F2RL3 | |
| SCHEMBL19782635 | 0.78 | F2RL3 (0.64) | F2RL3 | |
| SCHEMBL21395599 | 0.78 | F2RL3 (0.68) | F2RL3 | |
| SCHEMBL30187729 | 0.78 | F2RL3 (0.68) | F2RL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013774-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-01-18 | — | — | WO | disclosed |