SCHEMBL1978380

SCHEMBL1978380

c1ccc2c(c1)c1ccc3c4cccc5ccc6ccc7c2cc1c3c7c6c54

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.67
HSD17B10 Q99714 8/20 0.67
HPGD P15428 6/20 0.67
CYP1A2 P05177 5/20 0.67
THRB P10828 1/20 0.67
ERBB2 P04626 1/20 0.59
FYN P06241 1/20 0.59
MAOA P21397 1/20 0.59
ACHE P22303 1/20 0.59
AHR P35869 1/20 0.59
HPRT1 P00492 4/20 0.46
TSHR P16473 5/20 0.42
CYP3A4 P08684 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
CYP1B1 Q16678 2/20 0.40
CYP1A1 P04798 1/20 0.40
HIF1A Q16665 3/20 0.39
MAPK1 P28482 2/20 0.39
CASP1 P29466 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5482548 0.94 ALDH1A1 (0.64) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL29587575 0.91 HSD17B10 (0.80) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL4853454 0.91 HSD17B10 (0.80) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL4853640 0.91 HSD17B10 (0.80) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL4845123 0.90 HSD17B10 (0.64) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL4854579 0.89 ALDH1A1 (0.62) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL4847683 0.89 HSD17B10 (0.76) ALDH1A1HSD17B10HPGDCYP1A2THRB
Pyrene SCHEMBL6701359 0.89 ALDH1A1 (0.68) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL4848741 0.89 ALDH1A1 (0.84) ALDH1A1HSD17B10HPGDCYP1A2THRB
SCHEMBL4855368 0.88 HSD17B10 (0.61) ALDH1A1HSD17B10HPGDCYP1A2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2260035-B1 POLYCYCLIC ORGANIC COMPOUNDS, POLARIZING ELEMENTS AND METHOD OF PRODUCTION THEREOF CRYSOPTIX KK (JP) 2014-08-20 EP claimed
US-20110149393-A1 Polycyclic Organic Compounds, Polarizing Elements and Method of Production Thereof Crysoptic KK (JP) 2011-06-23 US claimed
EP-2260035-A2 POLYCYCLIC ORGANIC COMPOUNDS, POLARIZING ELEMENTS AND METHOD OF PRODUCTION THEREOF CRYSOPTIX K.K. (JP) 2010-12-15 EP claimed
WO-2009109781-A2 POLYCYCLIC ORGANIC COMPOUNDS, POLARIZING ELEMENTS AND METHOD OF PRODUCTION THEREOF CRYSOPTIX K.K. (JP) 2009-09-11 WO claimed
EP-2260035-B1 POLYCYCLIC ORGANIC COMPOUNDS, POLARIZING ELEMENTS AND METHOD OF PRODUCTION THEREOF CRYSOPTIX KK (JP) 2014-08-20 EP disclosed
US-20120222794-A1 TRANSFER SUBSTRATE AND METHOD FOR FABRICATING ORGANIC ELECTROLUMINESCENT ELEMENT SONY CORPORATION (JP) 2012-09-06 US disclosed
US-8207088-B2 Transfer substrate and method for fabricating organic electroluminescent element SONY CORPORATION (JP) 2012-06-26 US disclosed
US-20110149393-A1 Polycyclic Organic Compounds, Polarizing Elements and Method of Production Thereof Crysoptic KK (JP) 2011-06-23 US disclosed
EP-2260035-A2 POLYCYCLIC ORGANIC COMPOUNDS, POLARIZING ELEMENTS AND METHOD OF PRODUCTION THEREOF CRYSOPTIX K.K. (JP) 2010-12-15 EP disclosed
WO-2009109781-A2 POLYCYCLIC ORGANIC COMPOUNDS, POLARIZING ELEMENTS AND METHOD OF PRODUCTION THEREOF CRYSOPTIX K.K. (JP) 2009-09-11 WO disclosed
US-20090045735-A1 TRANSFER SUBSTRATE AND METHOD FOR FABRICATING ORGANIC ELECTROLUMINESCENT ELEMENT SONY CORPORATION (JP) 2009-02-19 US disclosed
EP-1359790-B1 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK CO (US) 2008-10-29 EP disclosed
US-7183010-B2 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK CORPORATION (US) 2007-02-27 US disclosed
US-7175922-B2 Aggregate organic light emitting diode devices with improved operational stability EASTMAN KODAK COMPANY (US) 2007-02-13 US disclosed
US-20050106415-A1 Aggregate organic light emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2005-05-19 US disclosed
US-20040076853-A1 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2004-04-22 US disclosed
EP-1359790-A2 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK COMPANY (US) 2003-11-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110149393-A1 Polycyclic Organic Compounds, Polarizing Elements and Method of Production Thereof CCNB1, CCNB2, CCNE2 ALDH1A1 3686/4885HSD17B10 3435/4885HPGD 1463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.