Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 1/20 | 0.34 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.34 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 4/20 | 0.32 |
| ▸ | JAK3 | P52333 | 4/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19783927 | 0.93 | ULK1 (0.35) | ULK1ULK2MKNK2STK17ASLC22A2 | |
| SCHEMBL21220085 | 0.93 | ULK1 (0.35) | ULK1ULK2MKNK2STK17ASLC22A2 | |
| SCHEMBL19783930 | 0.93 | ULK1 (0.35) | ULK1ULK2MKNK2STK17ASLC22A2 | |
| SCHEMBL19783929 | 0.93 | ULK1 (0.35) | ULK1ULK2MKNK2STK17ASLC22A2 | |
| SCHEMBL21220035 | 0.93 | ULK1 (0.35) | ULK1ULK2MKNK2STK17ASLC22A2 | |
| SCHEMBL22590970 | 0.91 | ULK1 (0.35) | ULK1ULK2MKNK2STK17AP2RX7 | |
| SCHEMBL19784186 | 0.88 | TRPV1 (0.36) | P2RX7KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL19783507 | 0.88 | ULK1 (0.38) | ULK1ULK2MKNK2STK17ASLC22A2 | |
| SCHEMBL19783509 | 0.88 | ULK1 (0.38) | ULK1ULK2MKNK2STK17ASLC22A2 | |
| SCHEMBL19784061 | 0.88 | ULK1 (0.32) | ULK1ULK2MKNK2STK17ASLC22A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018011017-A1 | 7-SUBSTITUTED 1-PYRIDYL-NAPHTHYRIDINE-3-CARBOXYLIC ACID AMIDES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-01-18 | — | — | WO | disclosed |