Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | CPN1 | P15169 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27774723 | 0.94 | CYP2C19 (0.52) | TBXAS1CYP2C19SRCCYP2D6POLB | |
| SCHEMBL14360139 | 0.90 | TBXAS1 (0.60) | TBXAS1CYP2C19SRCCYP2D6POLB | |
| SCHEMBL15717090 | 0.89 | HDAC7 (0.42) | TBXAS1CYP2C19SRCCYP2D6POLB | |
| Ammonia Solution, Strong SCHEMBL28556745 | 0.88 | TBXAS1 (0.59) | TBXAS1CYP2C19SRCCYP2D6POLB | |
| Ammonia Solution, Strong SCHEMBL28562956 | 0.88 | TBXAS1 (0.59) | TBXAS1CYP2C19SRCCYP2D6POLB | |
| SCHEMBL7899585 | 0.86 | CYP2C19 (0.55) | TBXAS1CYP2C19SRCCYP2D6POLB | |
| SCHEMBL7909074 | 0.86 | CYP2C19 (0.55) | TBXAS1CYP2C19SRCCYP2D6POLB | |
| SCHEMBL819393 | 0.86 | CYP2C19 (0.55) | TBXAS1CYP2C19SRCCYP2D6POLB | |
| SCHEMBL962850 | 0.85 | TBXAS1 (0.52) | TBXAS1CYP2C19SRCCYP2D6POLB | |
| SCHEMBL30371912 | 0.83 | CYP2C19 (0.61) | TBXAS1CYP2C19SRCCYP2D6POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2504328-A1 | NOVEL COMPOUNDS AS RECEPTOR MODULATORS WITH THERAPEUTIC UTILITY | Allergan, Inc. (US) | 2012-10-03 | — | — | EP | disclosed |
| WO-2011066179-A1 | NOVEL COMPOUNDS AS RECEPTOR MODULATORS WITH THERAPEUTIC UTILITY | ALLERGAN, INC. (US) | 2011-06-03 | — | — | WO | disclosed |